| 1 |
<?xml version="1.0" encoding="UTF-8" ?> |
| 2 |
<!DOCTYPE CDXML SYSTEM "http://www.cambridgesoft.com/xml/cdxml.dtd" > |
| 3 |
<CDXML |
| 4 |
CreationProgram="ChemDraw 13.0.2.3020" |
| 5 |
Name="Untitled Document-2" |
| 6 |
BoundingBox="84 304.45 274.50 450.88" |
| 7 |
WindowPosition="0 0" |
| 8 |
WindowSize="0 0" |
| 9 |
FractionalWidths="yes" |
| 10 |
InterpretChemically="yes" |
| 11 |
ShowAtomQuery="yes" |
| 12 |
ShowAtomStereo="no" |
| 13 |
ShowAtomEnhancedStereo="yes" |
| 14 |
ShowAtomNumber="no" |
| 15 |
ShowResidueID="no" |
| 16 |
ShowBondQuery="yes" |
| 17 |
ShowBondRxn="yes" |
| 18 |
ShowBondStereo="no" |
| 19 |
ShowTerminalCarbonLabels="no" |
| 20 |
ShowNonTerminalCarbonLabels="no" |
| 21 |
HideImplicitHydrogens="no" |
| 22 |
Magnification="166" |
| 23 |
LabelFont="21" |
| 24 |
LabelSize="10" |
| 25 |
LabelFace="96" |
| 26 |
CaptionFont="20" |
| 27 |
CaptionSize="12" |
| 28 |
HashSpacing="2.70" |
| 29 |
MarginWidth="2" |
| 30 |
LineWidth="1" |
| 31 |
BoldWidth="4" |
| 32 |
BondLength="30" |
| 33 |
BondSpacing="12" |
| 34 |
ChainAngle="120" |
| 35 |
LabelJustification="Auto" |
| 36 |
CaptionJustification="Left" |
| 37 |
AminoAcidTermini="HOH" |
| 38 |
ShowSequenceTermini="yes" |
| 39 |
ShowSequenceBonds="yes" |
| 40 |
ResidueWrapCount="40" |
| 41 |
ResidueBlockCount="10" |
| 42 |
ResidueZigZag="yes" |
| 43 |
NumberResidueBlocks="no" |
| 44 |
PrintMargins="36 36 36 36" |
| 45 |
MacPrintInfo="00030000004800480000000002DE0240FFEEFFEE030602520367052803FC00020000004800480000000002D802280001000000640000000100030303000000017FFF000100010000000000000000000000006808001901900000000000200000000000000000000000000000000000000000000000000000" |
| 46 |
ChemPropName="" |
| 47 |
ChemPropFormula="Chemical Formula: " |
| 48 |
ChemPropExactMass="Exact Mass: " |
| 49 |
ChemPropMolWt="Molecular Weight: " |
| 50 |
ChemPropMOverZ="m/z: " |
| 51 |
ChemPropAnalysis="Elemental Analysis: " |
| 52 |
ChemPropBoilingPt="Boiling Point: " |
| 53 |
ChemPropMeltingPt="Melting Point: " |
| 54 |
ChemPropCritTemp="Critical Temp: " |
| 55 |
ChemPropCritPres="Critical Pres: " |
| 56 |
ChemPropCritVol="Critical Vol: " |
| 57 |
ChemPropGibbs="Gibbs Energy: " |
| 58 |
ChemPropLogP="Log P: " |
| 59 |
ChemPropMR="MR: " |
| 60 |
ChemPropHenry="Henry's Law: " |
| 61 |
ChemPropEForm="Heat of Form: " |
| 62 |
ChemProptPSA="tPSA: " |
| 63 |
color="0" |
| 64 |
bgcolor="1" |
| 65 |
><colortable> |
| 66 |
<color r="1" g="1" b="1"/> |
| 67 |
<color r="0" g="0" b="0"/> |
| 68 |
<color r="1" g="0" b="0"/> |
| 69 |
<color r="1" g="1" b="0"/> |
| 70 |
<color r="0" g="1" b="0"/> |
| 71 |
<color r="0" g="1" b="1"/> |
| 72 |
<color r="0" g="0" b="1"/> |
| 73 |
<color r="1" g="0" b="1"/> |
| 74 |
<color r="0.9891" g="0.4159" b="0.4345"/> |
| 75 |
</colortable><fonttable> |
| 76 |
<font id="20" charset="x-mac-roman" name="Times"/> |
| 77 |
<font id="21" charset="x-mac-roman" name="Helvetica"/> |
| 78 |
<font id="23" charset="x-mac-roman" name="Symbol"/> |
| 79 |
</fonttable><page |
| 80 |
id="35" |
| 81 |
BoundingBox="0 0 540 720" |
| 82 |
HeaderPosition="36" |
| 83 |
FooterPosition="36" |
| 84 |
PrintTrimMarks="yes" |
| 85 |
HeightPages="1" |
| 86 |
WidthPages="1" |
| 87 |
><fragment |
| 88 |
id="3" |
| 89 |
BoundingBox="93.40 342.23 136.19 354.49" |
| 90 |
Z="285" |
| 91 |
><n |
| 92 |
id="2" |
| 93 |
p="130.06 348.89" |
| 94 |
Z="284" |
| 95 |
LabelSize="14" |
| 96 |
LabelFace="65535" |
| 97 |
Element="7" |
| 98 |
NumHydrogens="0" |
| 99 |
NeedsClean="yes" |
| 100 |
AS="N" |
| 101 |
><t |
| 102 |
p="126.08 353.91" |
| 103 |
BoundingBox="126.08 342.25 136.19 353.91" |
| 104 |
LabelSize="14" |
| 105 |
LabelFace="65535" |
| 106 |
LabelJustification="Left" |
| 107 |
><s font="21" size="14" color="0" face="96">N</s></t></n><n |
| 108 |
id="4" |
| 109 |
p="97.85 349.22" |
| 110 |
Z="286" |
| 111 |
Warning="An atom in this label has an invalid valence." |
| 112 |
LabelSize="14" |
| 113 |
LabelFace="65535" |
| 114 |
NumHydrogens="0" |
| 115 |
NeedsClean="yes" |
| 116 |
AS="N" |
| 117 |
><t |
| 118 |
p="93.40 354.24" |
| 119 |
BoundingBox="93.40 342.23 103.51 354.49" |
| 120 |
LabelSize="14" |
| 121 |
LabelFace="65535" |
| 122 |
LabelJustification="Left" |
| 123 |
><s font="21" size="14" color="0" face="96">C</s></t></n><b |
| 124 |
id="5" |
| 125 |
Z="287" |
| 126 |
B="2" |
| 127 |
E="4" |
| 128 |
Order="3" |
| 129 |
BS="N" |
| 130 |
/></fragment><fragment |
| 131 |
id="9" |
| 132 |
BoundingBox="130.78 406.85 162.64 439.91" |
| 133 |
Z="289" |
| 134 |
><n |
| 135 |
id="8" |
| 136 |
p="156.52 413.49" |
| 137 |
Z="288" |
| 138 |
LabelSize="14" |
| 139 |
LabelFace="65535" |
| 140 |
Element="7" |
| 141 |
NumHydrogens="0" |
| 142 |
NeedsClean="yes" |
| 143 |
AS="N" |
| 144 |
><t |
| 145 |
p="152.53 418.51" |
| 146 |
BoundingBox="152.53 406.85 162.64 418.51" |
| 147 |
LabelSize="14" |
| 148 |
LabelFace="65535" |
| 149 |
LabelJustification="Left" |
| 150 |
><s font="21" size="14" color="0" face="96">N</s></t></n><n |
| 151 |
id="10" |
| 152 |
p="135.24 434.64" |
| 153 |
Z="290" |
| 154 |
Warning="An atom in this label has an invalid valence." |
| 155 |
LabelSize="14" |
| 156 |
LabelFace="65535" |
| 157 |
NumHydrogens="0" |
| 158 |
NeedsClean="yes" |
| 159 |
AS="N" |
| 160 |
><t |
| 161 |
p="130.78 439.66" |
| 162 |
BoundingBox="130.78 427.64 140.89 439.91" |
| 163 |
LabelSize="14" |
| 164 |
LabelFace="65535" |
| 165 |
LabelJustification="Left" |
| 166 |
><s font="21" size="14" color="0" face="96">C</s></t></n><b |
| 167 |
id="11" |
| 168 |
Z="294" |
| 169 |
B="8" |
| 170 |
E="10" |
| 171 |
Order="3" |
| 172 |
BS="N" |
| 173 |
/></fragment><t |
| 174 |
id="20" |
| 175 |
p="112.83 381.17" |
| 176 |
BoundingBox="112.83 372.17 122.50 386.47" |
| 177 |
Z="292" |
| 178 |
color="8" |
| 179 |
Warning="Chemical Interpretation is not possible for this label" |
| 180 |
LineHeight="auto" |
| 181 |
><s font="20" size="12" color="8" face="3">r</s><s font="20" size="12" color="8" face="34">ij</s></t><t |
| 182 |
id="24" |
| 183 |
p="141.67 403" |
| 184 |
BoundingBox="141.67 390.88 150.42 406.62" |
| 185 |
Z="293" |
| 186 |
color="8" |
| 187 |
Warning="Chemical Interpretation is not possible for this label" |
| 188 |
LineHeight="auto" |
| 189 |
><s font="23" size="12" color="8">q</s><s font="20" size="12" color="8" face="34">i</s></t><t |
| 190 |
id="26" |
| 191 |
p="235 344.83" |
| 192 |
BoundingBox="235 332.72 243.23 348.45" |
| 193 |
Z="295" |
| 194 |
color="8" |
| 195 |
Warning="Chemical Interpretation is not possible for this label" |
| 196 |
LineHeight="auto" |
| 197 |
><s font="23" size="12" color="8">w</s></t><graphic |
| 198 |
id="19" |
| 199 |
SupersededBy="36" |
| 200 |
BoundingBox="274.50 349 84 349" |
| 201 |
Z="262" |
| 202 |
color="10" |
| 203 |
LineWidth="0.50" |
| 204 |
LineType="Dashed" |
| 205 |
GraphicType="Line" |
| 206 |
/><graphic |
| 207 |
id="15" |
| 208 |
SupersededBy="37" |
| 209 |
BoundingBox="167 349 84 349" |
| 210 |
Z="277" |
| 211 |
color="4" |
| 212 |
GraphicType="Line" |
| 213 |
ArrowType="FullHead" |
| 214 |
HeadSize="1500" |
| 215 |
/><graphic |
| 216 |
id="31" |
| 217 |
BoundingBox="105.18 355.79 91.17 342.78" |
| 218 |
Z="278" |
| 219 |
color="1" |
| 220 |
GraphicType="Rectangle" |
| 221 |
RectangleType="Filled" |
| 222 |
Center3D="98.18 349.29 0" |
| 223 |
MajorAxisEnd3D="105.18 349.29 0" |
| 224 |
MinorAxisEnd3D="98.18 355.79 0" |
| 225 |
/><graphic |
| 226 |
id="18" |
| 227 |
SupersededBy="38" |
| 228 |
BoundingBox="259.50 310 120 450" |
| 229 |
Z="279" |
| 230 |
color="10" |
| 231 |
LineWidth="0.50" |
| 232 |
LineType="Dashed" |
| 233 |
GraphicType="Line" |
| 234 |
/><graphic |
| 235 |
id="16" |
| 236 |
SupersededBy="39" |
| 237 |
BoundingBox="184.12 385.88 120 450" |
| 238 |
Z="280" |
| 239 |
color="4" |
| 240 |
GraphicType="Line" |
| 241 |
ArrowType="FullHead" |
| 242 |
HeadSize="1500" |
| 243 |
/><graphic |
| 244 |
id="33" |
| 245 |
BoundingBox="148.01 436.47 127.47 436.72" |
| 246 |
Z="281" |
| 247 |
color="1" |
| 248 |
GraphicType="Rectangle" |
| 249 |
RectangleType="Filled" |
| 250 |
Center3D="137.74 436.60 0" |
| 251 |
MajorAxisEnd3D="142.81 429.73 0" |
| 252 |
MinorAxisEnd3D="142.94 443.34 0" |
| 253 |
/><graphic |
| 254 |
id="32" |
| 255 |
BoundingBox="166.78 412.88 146.25 413.07" |
| 256 |
Z="282" |
| 257 |
color="1" |
| 258 |
GraphicType="Rectangle" |
| 259 |
RectangleType="Filled" |
| 260 |
Center3D="156.51 412.97 0" |
| 261 |
MajorAxisEnd3D="161.58 407.79 0" |
| 262 |
MinorAxisEnd3D="161.71 418.06 0" |
| 263 |
/><graphic |
| 264 |
id="30" |
| 265 |
BoundingBox="134.85 353.96 124.21 343.28" |
| 266 |
Z="283" |
| 267 |
color="1" |
| 268 |
GraphicType="Rectangle" |
| 269 |
RectangleType="Filled" |
| 270 |
Center3D="129.53 348.62 0" |
| 271 |
MajorAxisEnd3D="134.85 348.62 0" |
| 272 |
MinorAxisEnd3D="129.53 353.96 0" |
| 273 |
/><graphic |
| 274 |
id="17" |
| 275 |
SupersededBy="40" |
| 276 |
BoundingBox="114.50 350 145 425" |
| 277 |
Z="291" |
| 278 |
color="8" |
| 279 |
GraphicType="Line" |
| 280 |
ArrowType="FullHead" |
| 281 |
HeadSize="1000" |
| 282 |
/><graphic |
| 283 |
id="27" |
| 284 |
BoundingBox="144.17 317.83 131.62 305.12" |
| 285 |
Z="296" |
| 286 |
color="1" |
| 287 |
GraphicType="Rectangle" |
| 288 |
RectangleType="Plain" |
| 289 |
Center3D="137.89 311.47 0" |
| 290 |
MajorAxisEnd3D="144.17 311.47 0" |
| 291 |
MinorAxisEnd3D="137.89 317.83 0" |
| 292 |
/><scheme |
| 293 |
id="41" |
| 294 |
><step |
| 295 |
id="42" |
| 296 |
ReactionStepProducts="3" |
| 297 |
ReactionStepArrows="17" |
| 298 |
ReactionStepObjectsBelowArrow="20" |
| 299 |
/></scheme><scheme |
| 300 |
id="43" |
| 301 |
><step |
| 302 |
id="44" |
| 303 |
ReactionStepProducts="9" |
| 304 |
ReactionStepArrows="15" |
| 305 |
/></scheme><arrow |
| 306 |
id="36" |
| 307 |
BoundingBox="84 348.75 274.50 349.25" |
| 308 |
Z="262" |
| 309 |
color="10" |
| 310 |
LineWidth="0.50" |
| 311 |
LineType="Dashed" |
| 312 |
FillType="None" |
| 313 |
ArrowheadType="Solid" |
| 314 |
Head3D="274.50 349 0" |
| 315 |
Tail3D="84 349 0" |
| 316 |
Center3D="316.50 519.25 0" |
| 317 |
MajorAxisEnd3D="507 519.25 0" |
| 318 |
MinorAxisEnd3D="316.50 709.75 0" |
| 319 |
/><arrow |
| 320 |
id="37" |
| 321 |
BoundingBox="84 345.07 167 352.76" |
| 322 |
Z="277" |
| 323 |
color="4" |
| 324 |
FillType="None" |
| 325 |
ArrowheadHead="Full" |
| 326 |
ArrowheadType="Solid" |
| 327 |
HeadSize="1500" |
| 328 |
ArrowheadCenterSize="1313" |
| 329 |
ArrowheadWidth="375" |
| 330 |
Head3D="167 349 0" |
| 331 |
Tail3D="84 349 0" |
| 332 |
Center3D="209 523.50 0" |
| 333 |
MajorAxisEnd3D="292 523.50 0" |
| 334 |
MinorAxisEnd3D="209 606.50 0" |
| 335 |
/><arrow |
| 336 |
id="38" |
| 337 |
BoundingBox="119.82 309.82 259.68 450.18" |
| 338 |
Z="279" |
| 339 |
color="10" |
| 340 |
LineWidth="0.50" |
| 341 |
LineType="Dashed" |
| 342 |
FillType="None" |
| 343 |
ArrowheadType="Solid" |
| 344 |
Head3D="259.50 310 0" |
| 345 |
Tail3D="120 450 0" |
| 346 |
Center3D="321.75 536 0" |
| 347 |
MajorAxisEnd3D="519.39 536 0" |
| 348 |
MinorAxisEnd3D="321.75 733.64 0" |
| 349 |
/><arrow |
| 350 |
id="39" |
| 351 |
BoundingBox="119.65 385.52 184.48 450.35" |
| 352 |
Z="280" |
| 353 |
color="4" |
| 354 |
FillType="None" |
| 355 |
ArrowheadHead="Full" |
| 356 |
ArrowheadType="Solid" |
| 357 |
HeadSize="1500" |
| 358 |
ArrowheadCenterSize="1313" |
| 359 |
ArrowheadWidth="375" |
| 360 |
Head3D="184.12 385.88 0" |
| 361 |
Tail3D="120 450 0" |
| 362 |
Center3D="244.12 610.88 0" |
| 363 |
MajorAxisEnd3D="334.81 610.88 0" |
| 364 |
MinorAxisEnd3D="244.12 701.56 0" |
| 365 |
/><arrow |
| 366 |
id="40" |
| 367 |
BoundingBox="114.04 349.81 145.46 425.19" |
| 368 |
Z="291" |
| 369 |
color="8" |
| 370 |
FillType="None" |
| 371 |
ArrowheadHead="Full" |
| 372 |
ArrowheadType="Solid" |
| 373 |
HeadSize="1000" |
| 374 |
ArrowheadCenterSize="875" |
| 375 |
ArrowheadWidth="250" |
| 376 |
Head3D="114.50 350 0" |
| 377 |
Tail3D="145 425 0" |
| 378 |
Center3D="187 562.50 0" |
| 379 |
MajorAxisEnd3D="267.96 562.50 0" |
| 380 |
MinorAxisEnd3D="187 643.46 0" |
| 381 |
/></page></CDXML> |
