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lipid bilayers. in the past, researchers have approached this problem |
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from two different approaches. The first, is complete specification of |
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a factual phospholipid, an all-atom model. All-atom models have been |
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used with success in systems of ({\color{red} LIST OF CITATIONS}). |
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used with success in systems of ({\color{red} LIST OF |
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CITATIONS}). These simulations have been limited in their size and |
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time scales due to the amount od information calculated at every |
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integration step. Typically these simulations have $\sim64$~lipids |
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with roughly 25~waters for every |
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lipid\cite{saiz02,lindahl00,venable00,Marrink01}. This means there are |
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on the order of 8,000 atoms needed to simulate these systems. The |
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amount of calculation required limits the length of time all-atom |
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simulations may run. Processor power is continually increasing, however, these simulations typically run for times up to 10~ns.{\color{red}CITE ME} |
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|
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A second popular approach is to the phospholipid |